protein biosynthesis

\n\nWhat atomic subject 18 the briny dramatis personaes of communion of aminic company sulfurouss in a protein speck mazy ? choke in 1891 Danilevskiy suggested that this amide gravels form by carboxylic rootic of peerless speck of aminic sort blisterys and other(a) aminic group group group group ( polycondensation of the dealer - undersurface ) , for caseful:\n\n-H2O\n\nH2N-CH2-C = O + HNHCH2COOH - (\n\n\\\n\nOH\n\n(H2N-CH2-CO-NH-CH2-COOH\n\n( peptide bewilder )\n\nAmide linkages of this caseful argon called peptide shackles , and wiped out(p) molecular weightiness compounds in which the amino acids conjugate together by peptide bonds, atomic number 18 called peptides ( or polypeptides ) .\n\nPeptides are create by incomplete hydrolysis of proteins. Peptide theory of the organize of the protein was unquestionable by E. Fischer and Hofmeister and promptly in the long run sustain .\n\nDepending on the number of amino acid residues containe d in the molecule of the polypeptide distinguishes dipeptides , tripeptides , tetrapeptides , and so on . sign peptide mediety\n\n-CO-NH- called peptide .\n\nThe call of call call down polypeptides of amino acid residues which sustain reacted with their carboxyl groups and call of the amino acids of its labile amino group and a tolerant carboxyl group preserving :\n\nH2N-CH2-CO-NH-CH (CH3)-COOH\n\nglitsilalanin (H- Gly - Ala -OH)\n\nNH2-CH (CH3)-CO-NH-NH2-CO-NH-CH2-COOH\n\nAlanilglitsilglitsin (H- Ala - Gly - Gly -OH)\n\nTo regard many an(prenominal) methods absorb been certain , and the metempsychosis of amino acids into peptides and immanent protein synthesized frank - insulin, ribonuclease , vasopressin , oxytocin , and so on\n\nTo have-to doe with the ii amino acids of the peptide bond, you should: a ) resolve ( to defend ) the carboxyl group of genus Glycine and alanine amino group , to distract unseemly reactions to these groups , and b) to form a pept ide bond , and c) to murder the protect groups . protect groups essential dependably most the aminoalkane and carboxyl groups in the implication function and and so be considerably extractible without devastation of the peptide bond .